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ASTM E2888-12(2019)

ASTM E2888-12(2019)

Standard Practice for Process for Inactivation of Rodent Retrovirus by pH

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1.1 ,This practice assures 5 log10 inactivation of non-defective C-type retroviruses, which are endogenous to murine hybridoma and CHO cells and are potentially present in the production stream of biopharmaceutical processes that use rodent derived cell culture.

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